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  2. 四神丸



  1. Sishen Wan

The Prescription of 四神丸


The book Zheng Zhi Zhun Sheng



Bu Gu Zhi: The principal drug, warming and tonifying the kidney-Yang.

Rou Dou Kou: Warming the spleen to arrest diarrhea, promoting the flow of Qi and removing stagnated food.

Wu Zhu Yu and Sheng Jiang: Warming the middle-Jiao to expel pathogenic cold.

Wu Wei Zi: Astringing the intestines to arrest diarrhea.

Da Zao: Tonifying the spleen and benefiting the stomach.

The Effect of 四神丸


Warming and tonifying the spleen and kidney, astringing the intestines to arrest diarrhea.


Syndrome due to cold-deficiency of the spleen and kidney, marked by diarrhea before dawn, loss of appetite, abdominal pain, soreness of the loins, cold limbs, listlessness, lassitude, pale tongue with thin whitish coating, and deep slow weak pulse; including such diseases with the above symptoms as chronic colitis, allergic colitis and intestinal tuberculosis.


Da Zao without the cores is boiled up to being done, The other ingredients are ground into fine powder, which is mixed with the boiled Da Zao mo pills. 6-9 g of the pills is taken each time, twice daily. Or all the ingredients are decocted in water for oral dose after the amounts of the drugs are reduced according to the proportions in the original prescription.